Resistance to radiation and chemotherapy in colorectal cancer (CRC) patients contribute significantly to refractory disease and disease progression.Herein, we provide mechanistic rationale for acquired or inherent chemotherapeutic resistance to the anti-tumor effects of 5-fluorouracil (5-FU) that is linked to oncogenic GLI1 transcription activity a
With rapid urbanization, hazardous environmental exposures such as air, noise, plastic, soil and water pollution have emerged as a major threat to urban health.Recent studies show that 9 out of 10 people worldwide breathe contaminated air contributing to over 7 million premature deaths annually.Internet of Things (IoT) and Artificial Intelligence (
A high-throughput cross-layer optimization strategy based on the interference management for the multi-hop multi-base-station wireless network environment was proposed.In the physical layer the successive interference cancella-tion was used to realize the interference management.In the up layers,first the Voronoi algorithm was used to Battery Box C
Abstract Background Lateral periodontal cyst (LPC) is an uncommon form of developmental odontogenic cyst.LPC can be suspected when there is a round, well-circumscribed radiolucency, usually of small diameter, along the lateral surface of vital erupted teeth, predominantly in the mandibular premolar region.Histopathological analysis allows LPC to be
Brassinosteroids (BRs) regulate rice plant architecture, including leaf bending, which affects grain yield.Although BR signaling has been investigated in Arabidopsis thaliana, the components negatively regulating this pathway are less well understood.Here, we demonstrate that Oryza sativa LEAF and TILLER ANGLE INCREASED CONTROLLER (LIC) Travel acts